Health Guide

Ioversol (By injection)

Ioversol (eye-oh-VER-sol)

Used during angiography or CT scan to help the head, heart, or other parts of the body show up better.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to ioversol, or if you have an overactive thyroid.

How to Use This Medicine:


  • A nurse or other health provider will give you this medicine. This medicine is given through a needle placed in an artery or a vein.
  • Drink extra fluids so you will urinate more often and help prevent kidney problems.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how ioversol works. Tell your doctor if you are using metformin.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, asthma, allergies, blood clotting problems, congestive heart failure, diabetes, heart or blood vessel disease, high blood pressure, thyroid problems, adrenal problems (including pheochromocytoma), blood disorders (including paraproteinemia, sickle cell disease), or trouble urinating. Tell your doctor if you had an allergic reaction to iodine or any contrast agent. Tell your doctor if you have an inherited disease called homocystinuria.
  • This medicine may cause the following problems:
    • Increased risk of heart attack, stroke, or blood clotting problems (during angiographic procedures)
    • Kidney problems
    • Serious skin reactions
    • Drug reaction with eosinophilia and systemic symptoms (DRESS)
  • Tell any doctor who treats you that you have been given this medicine. It can affect certain medical tests for a short period after you receive it.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, faintness
  • Coughing up blood
  • Decrease in how much or how often you urinate, confusion, dizziness, swelling in your hands, ankles, or feet
  • Muscle weakness, stiff joints or trouble moving, bone pain
  • Numbness or weakness in your arm or leg, or on one side of your body, sudden or severe headache, problems with vision, speech, or walking

If you notice these less serious side effects, talk with your doctor:

  • Pain, itching, burning, redness, peeling, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 7/4/2018
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