Health Guide

Iohexol (By injection)

Iohexol (eye-oh-HEX-ol)

Used to help create pictures of the body during a medical imaging procedure.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to iohexol.

How to Use This Medicine:


  • A doctor or other health professional will give you this medicine before the imaging procedure. It is usually given as a shot into a vein.
  • Drink plenty of fluids before and after receiving this medicine as a shot so you will pass more urine. This may help prevent kidney problems.
  • You may also receive other medicines (including allergy medicine, steroids) to prevent allergic reactions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how iohexol works. Tell your doctor if you are using any of the following:
    • Metformin
    • Beta blocker medicine
    • Medicine to treat depression or other mental problems (including an MAO inhibitor or phenothiazine)

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, adrenal problems (including pheochromocytoma), sickle cell disease, multiple myeloma, congestive heart failure, diabetes, heart or blood vessel disease, high blood pressure, or thyroid disease. Tell your doctor if you drink alcohol, or if you have a history of asthma.
  • This medicine may cause the following problems:
    • Heart or blood vessel disease (including heart attack)
    • Kidney problems
    • Serious skin reactions
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Back pain, neck pain or stiffness
  • Blistering, peeling, red skin rash
  • Change in how much or how often you urinate
  • Chest pain, trouble breathing, or coughing up blood
  • Dizziness, lightheadedness, fainting, fast or shallow breathing
  • Fast, slow, or uneven heartbeat
  • Muscle pain, tenderness, or weakness
  • Numbness or weakness in your arm or leg or on one side of your body
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Pain in your lower leg (calf)
  • Pain, redness, or swelling at the injection site
  • Seizures, drowsiness, changes in vision
  • Sudden or severe headache

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, gas, stomach pain
  • Itching, burning, or warmth where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 7/4/2018
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