Health Guide

Lacosamide (By injection)

Lacosamide (la-KOE-sa-mide)

Treats partial seizures.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to lacosamide.

How to Use This Medicine:


  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how lacosamide works. Tell your doctor if you are using blood pressure medicine.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetic neuropathy, or any heart problems. Tell your doctor if you have a history of depression or mental health problems.
  • This medicine may cause the following problems:
    • Changes in heart rhythm (such as PR prolongation)
    • Serious allergic reactions that may involve multiple organs, such as your liver or kidneys
    • Change in mood or unusual thoughts
  • This medicine may make you dizzy or drowsy, or cause double vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Bloody or cloudy urine, rapid weight gain, swelling of your face, feet, or lower legs
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Depression, unusual changes in mood or behavior, or thoughts of hurting yourself
  • Fast, slow, pounding, or uneven heartbeat
  • Fever, rash, swollen, painful, or tender lymph glands in your neck, armpit, or groin
  • Lightheadedness or dizziness
  • Problems with walking or balance, sleepiness, blurred or double vision
  • Trouble breathing, fainting

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea
  • Dry mouth
  • Headache
  • Increased sweating
  • Pain, redness, or irritation where the needle is placed
  • Tiredness or weakness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 7/4/2018
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