Health Guide

Tetanus immune globulin (By injection)

Tetanus Immune Globulin (TET-a-nus i-MUNE GLOB-ue-lin)

Protects against tetanus (the bacteria that causes lockjaw).

Brand Name(s):

HyperTET S/D

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Tell your doctor if you have had an allergic reaction to any tetanus vaccine or to medicine with human immune globulin (such as gamma globulin, IVIG). This will help your doctor decide if this medicine is right for you.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other trained health professional will give you this medicine.
  • This medicine may be given with another vaccine that also protects against tetanus.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • The following vaccines may not work as well if you receive them shortly after your tetanus shot: Measles, mumps, rubella (MMR), or polio. Talk to your doctor before getting other vaccines within 3 months after receiving tetanus immune globulin.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have any unusual bleeding or bruising.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Bloated feeling, swelling in your hands, ankles, or feet
  • Cloudy or foamy urine, decrease in how much or how often you urinate
  • Loss of appetite

If you notice these less serious side effects, talk with your doctor:

  • Mild fever, pain, or soreness where the shot is given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 7/4/2018
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