Health Guide

Poliovirus vaccine inactivated (By injection)

Poliovirus Vaccine, Inactivated (POE-lee-oh VYE-rus VAX-een, in-AK-ti-vated)

Prevents infections caused by polio virus.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive this vaccine if you had an allergic reaction to polio vaccine, neomycin, streptomycin, or polymyxin B.

How to Use This Medicine:


  • A nurse or other health provider will give you this medicine.
  • This medicine is given as a shot under your skin or into one of your muscles. In infants and small children, the shot is usually given in the thigh. In adults, the shot is usually given in the upper arm.
  • Children should receive a total of 4 doses of polio vaccine, usually at 6 weeks to 2 months, 4 months, 6 to 18 months, and 4 to 6 years of age.
  • Missed dose: This vaccine needs to be given on a fixed schedule. If a dose is missed, call your doctor to make another appointment as soon as possible.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some foods and medicines can affect how polio vaccine works. Tell your doctor if you are also receiving any treatment that affects your immune system, such as cancer medicine, steroid medicine, or radiation therapy.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding.
  • Tell your doctor if you have a fever, infection, or any condition that affects the immune system.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • High fever (over 102 degrees F)
  • Unusual weakness or numbness

If you notice these less serious side effects, talk with your doctor:

  • Nausea or vomiting
  • Pain, redness, swelling, or a lump where the shot was given
  • Sleepiness or irritability

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 7/4/2018
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