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Phytonadione (By injection)

Phytonadione (fye-toe-na-DYE-one)

Prevents bleeding problems by helping blood clot better. Also treats or prevents bleeding problems in newborn infants.

Brand Name(s):

Vitamin K1 Novaplus

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to phytonadione or vitamin K.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin, into a muscle, or into a vein.
  • A nurse or other health provider will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • Check the medicine before using. It should be clear and yellow. Do not use it if it is discolored or has particles in it.
  • You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
  • Use a new needle and syringe each time you inject your medicine.
  • Your doctor may also give you plasma or other blood products in addition to vitamin K if your bleeding is severe.
  • Missed dose: Call your doctor or pharmacist for instructions.
  • If you store this medicine at home, keep it at room temperature, away from heat and direct light.
  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how this medicine works. Tell your doctor if you are using a blood thinner, including warfarin.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, kidney disease, or if you have a problem with blood clotting too much (which can lead to a stroke).
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, sudden headache, trouble breathing, pain in your leg
  • Lightheadedness, dizziness, fainting
  • Rash

If you notice these less serious side effects, talk with your doctor:

  • Change in sense of taste
  • Redness, pain, swelling, or a hard lump where the injection was given
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 7/4/2018
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